CYP3A4-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR190
Cell Type: M1 macrophages
RNA writers: NSUN4
RNA readers: YTHDF2
RNA erasers: TET1/2/3
Enzymes: ALKBH5
RNA types: mRNAs
Modification: ac4C
RNA editing: A to I
Short Description
This product is a CYP3A4-targeted RNA modification and metabolomics analysis tool based on the ac4C (NSUN4-YTHDF2-TET1/2/3-ALKBH5-TET) modification and Gluconeogenesis-mediated (α-synuclein-SAM-ADP) metabolic analysis system.
RNA writers
NSUN4
RNA readers
YTHDF2
RNA erasers
TET1/2/3
Enzymes
ALKBH5
RNA types
mRNAs
Modification
ac4C
Label
TET
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-MOE, GalNAc
RNA Construction
mRNAs-ac4C-NSUN4-YTHDF2-TET1/2/3-ALKBH5-TET
Substrates
SAM
Cofactors
ADP
Pathway
Gluconeogenesis
Epigenetic regulator
NSD2 overexpression
Metabolic alteration
Upregulating pentose phosphate pathway
Targeting diseases
Pancreatic Cancer
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
Gluconeogenesis-α-synuclein-SAM-ADP
Target
CYP3A4
Alternative Names
Cytochrome P450 3A4; CYP3A4
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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