DNMT/mIDH2-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR12
Cell Type: M1 macrophages
RNA writers: METTL14
RNA readers: YTHDF2
RNA erasers: ALKBH5
Enzymes: FDH
RNA types: rRNA
Modification: ac4C
RNA editing: T to C
Short Description
This product is a DNMT/mIDH2-targeted RNA modification and metabolomics analysis tool based on the ac4C (METTL14-YTHDF2-ALKBH5-FDH-phos) modification and TCA cycle-mediated (α-synuclein-Lactyl-CoA-NAD+) metabolic analysis system.
RNA writers
METTL14
RNA readers
YTHDF2
RNA erasers
ALKBH5
Enzymes
FDH
RNA types
rRNA
Modification
ac4C
Label
phos
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
PS, 2'-OMe, 2'-F, GalNAc
RNA Construction
rRNA-ac4C-METTL14-YTHDF2-ALKBH5-FDH-phos
Substrates
Lactyl-CoA
Cofactors
NAD+
Pathway
TCA cycle
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Prostate Cancers
RNA-binding proteins
α-synuclein
Metabolic Reprogramming
TCA cycle-α-synuclein-Lactyl-CoA-NAD+
Target
DNMT/mIDH2
Alternative Names
DNMT/mIDH2
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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