PharmaOnco™ CHO-Tg(Human PSMA) Stable Cell Line, Single Clone

CAT#: ITS-0822-HMM198
Product Type: Stable Cell Line
Short Description
Creative Biolabs offers CHO-Tg(Human PSMA) stable cell line which the PSMA gene stably expressed in CHO cells.
Description
CHO-Tg (Human PSMA) stable cell line refers to a cell line derived from Chinese hamster ovary cells that have been genetically modified to express the human prostate-specific membrane antigen (PSMA). PSMA is a protein that is highly expressed in prostate cancer cells, making it a target for therapeutic interventions such as immunotherapy. These stable cell lines are used in research and drug development to study the role of PSMA in cancer progression and to test the efficacy of potential PSMA-targeted treatments.
Features
Consistent gene expression;
Reliability and reproducibility;
Applications
Functional assay
Protein Target
PSMA
Species
Human
Parental Cell Line
CHO
Gene
Genbank #NM_004476.1
Background
The PSMA gene, also known as the FOLH1 gene, codes for the prostate-specific membrane antigen (PSMA) protein. This protein is primarily expressed on the surface of prostate cancer cells and is often used as a target for imaging and therapeutic purposes in prostate cancer treatment. Mutations in the PSMA gene have been associated with increased risk of developing prostate cancer. Research into the PSMA gene and its role in prostate cancer continues to be an active area of study in the field of oncology.
Unit Size
1 x 10e6 cells/vial, Frozen
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Identity Testing
Identity testing is required for newly established cell lines. Isoenzyme analysis is used to confirm the identity of the species of a cell line. Alternative methods for identity testing include DNA fingerprinting, STR analysis and karyology.
Virological Safety Testing
A broad range of viruses is susceptible to affecting human cell lines. We can provide in vivo/vitro virus safety assays by utilizing various animal systems. These viruses include: adventitious viruses, bovine viruses, human and simian viruses, porcine viruses, retrovirus and rodent viruses.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Shipping
Dry Ice
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Research Use Only
For research use only, not for diagnostic or therapeutic use.
Quality Control
All of our stable cell lines meet the highest quality standards and have been confirmed to be pathogen-free.
For Research Use Only | Not For Clinical Use
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