Creative Biolabs offers HPV E7-Specific T cells for immunity reaserch.
Description
HPV E7-specific T cells are a type of immune cell that specifically targets and destroys cells infected with the human papillomavirus (HPV) E7 protein. These T cells play a crucial role in the body's immune response to HPV infections and can help eliminate HPV-infected cells to prevent the development of HPV-related diseases, such as cervical cancer.
Background
HPV E7-specific T cells are a type of immune cell that specifically targets cells infected with human papillomavirus (HPV) and expresses the viral protein E7. These T cells play a crucial role in the immune response against HPV, as they are able to recognize and destroy infected cells, preventing the virus from replicating and spreading. Research has shown that HPV E7-specific T cells can be harnessed for therapeutic purposes, such as in the development of immunotherapies for HPV-associated cancers, including cervical cancer and head and neck cancer. By boosting the activity of these T cells, it is possible to enhance the immune response against HPV-infected cells and improve patient outcomes.
Species
Human
Cell Type
T cell population
Culture medium
We recommend RPMI-1640 with 10% FBS media for our functional analysis, but that depends on the media used by customers for co-culturing experiments.
Features
High quality; High viability; Widely applications.
Survive Time
With proper stimulation, they will survive for about 4-5 days.
Antigen
HPV E7(82-90)
HLA Restricted
HLA-A*0201
Gender
Female
Donor Age
57
Donor Health
Normal
HLA-A
2:01:00
HLA-B
7:02:00
HLA-C
3:03:00
Blood Type
B-
Ethnicity
Caucasian
Anticoagulant
Acid-citrate-dextrose solution A (ACDA)
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>80%
Cell Viability
>80%
Mycoplasma Testing
Negative
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-198°C).
Handling Notes
Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.
Warnings
Avoid multiple freeze/thaw cycles.
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.