PharmaOnco™ Cynomolgus Monkey CD14+ Cells, Purified

CAT#: IC-LX037
Product Type: OncoImmune Cells
Cell Type: CD14+ Cells
Species: Cynomolgus Monkey
Short Description
Creative Biolabs offers Cynomolgus Monkey CD14+ Cells, Purified for immune reaserch.
Description
Cynomolgus Monkey CD14+ cells are isolated and purified immune cells that express the CD14 surface marker, commonly used in research studies to investigate immune response and inflammation in non-human primate models.
Species character
The cynomolgus macaque is the most commonly utilized non-human primate in biomedical research. According to some researchers, these monkeys are ideal models due to the 90-93% genetic similarity to and recent evolutionary divergence from humans. They are employed in numerous research areas, such as immunology, neuroscience, oncology, diabetes, and pharmacology due to their genetics and physiology.
Background
CD14+ cells make up approximately a third of cells in the blood of a typical adult monkey. Monocytes and neutrophils typically make up the cells that express CD14+ cells. When activated, monocytes can phagocytose foreign cells and perform antibody-dependent cellular phagocytosis (ADCP). They can also produce and secrete inflammatory cytokines. Developmentally, monocytes can mature into macrophages and dendritic cells depending on the soluble factors they are exposed to in order to become more specialized immune subsets.
Species
Cynomolgus Monkey
Cell Type
CD14+ Cells
Features
High quality;
High viability;
Widely applications.
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>95%
Cell Viability
>90%
Mycoplasma Testing
The cell line has been screened using the luciferase based mycoplasma detection kit to confirm the absence of mycoplasma species.
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Research Use Only
Our immune cell are for research use only, not for diagnostic or therapeutic use.
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Lyophilized cells should be stored in a liquid nitrogen tank (-150°C~-190°C). After thawing, cells should be immediately transferred to the appropriate culture medium and maintained under recommended culture conditions.
Handling Notes
Frozen cells should be thawed immediately upon receipt and grown according to handling procedure to ensure cell viability and proper assay performance.
Note: Do not freeze the cells upon receipt as it may result in irreversible damage to the cell line.
Disclaimer: We cannot guarantee cell viability if the cells are not thawed immediately upon receipt and grown according to handling procedure.
Warnings
Avoid multiple freeze/thaw cycles
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.
For Research Use Only | Not For Clinical Use
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