PharmaOnco™ Human Plasmacytoid Dendritic Cells, Peripheral Blood

Creative Biolabs offers Human Plasmacytoid Dendritic Cells, Peripheral Blood for drug discovery and toxicity testing, iImmunology.

Creative Biolabs provides a reliable ethically sourced, ready-to-use Human Plasmacytoid Dendritic Cells from Peripheral Blood. This product allows for study in numerous immunity research areas.

Plasmacytoid dendritic cells (pDCs) are a specialized subset of dendritic cells that play a key role in the innate immune response to viral infections. pDCs are known for their ability to produce large amounts of type I interferons, such as interferon-alpha, in response to viral stimuli. This can help to activate other immune cells and enhance the antiviral immune response. pDCs also have the ability to stimulate adaptive immune responses by presenting antigens to T cells. They can also interact with B cells to promote antibody production and aid in the development of long-lasting immune memory. In addition to their role in viral defense, pDCs have been implicated in the pathogenesis of autoimmune diseases, such as lupus and psoriasis. In these conditions, pDCs can produce excessive amounts of type I interferons, contributing to chronic inflammation and tissue damage

Human

B Cells

Peripheral blood

PRMI1640

High quality;
High viability;
Widely applications.

Normal

Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).

Contains Cryopreservation Medium

> 80%

Negative

Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.

We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.

All cells were collected under Institutional Review Board (IRB)-approved consent forms and protocols.

Immunotherapy Discovery and Development

Donors are negative for HIV-1, HIV-2, hepatitis B, and hepatitis C.

Stored at < -120°C once they are received.

Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.

Avoid multiple freeze/thaw cycles.

1 x 10e6 cells/vial

Frozen

Certain products are only available in select territories. Please contact us for more information.