Creative Biolabs offers MAGE A10-Specific T cells for immunity reaserch.
Description
MAGE A10-Specific T cells refer to T cells that are specifically engineered to recognize and target cells expressing the MAGE A10 protein. MAGE A10 is a tumor antigen that is commonly overexpressed in various cancers, making it a promising target for cancer immunotherapy. By engineering T cells to target MAGE A10, these cells can effectively seek out and destroy cancer cells expressing this antigen, leading to targeted and precise treatment of MAGE A10-positive cancers.
Background
MAGE A10-specific T cells are a type of immune cell that specifically recognizes and targets cells that express the MAGE A10 protein. This protein is often found in cancer cells and can serve as a target for immune-based therapies, such as adoptive T cell transfer. By isolating and expanding MAGE A10-specific T cells from a patient's own immune system, researchers can potentially enhance the body's ability to fight against cancer cells that express this protein.
Species
Human
Cell Type
T cell population
Culture medium
We recommend RPMI-1640 with 10% FBS media for our functional analysis, but that depends on the media used by customers for co-culturing experiments.
Features
High quality; High viability; Widely applications.
Survive Time
With proper stimulation, they will survive for about 4-5 days.
Antigen
MAGE A10
Gender
Female
Donor Age
31
Donor Health
Normal
HLA-A
2:01:03
HLA-B
18:01:00
HLA-C
3:04:00
Blood Type
A-
Ethnicity
Caucasian
Anticoagulant
Acid-citrate-dextrose solution A (ACDA)
Additional Donor Information
Contact us for donor specifications (Age,Gender,BMI category, smoking status, ethnicity, etc.).
Formulation
Contains Cryopreservation Medium
Cell Purity
>80%
Cell Viability
>80%
Mycoplasma Testing
Negative
Sterility Testing
Creative Biolabs provides sterility testing in accordance with USP and EP regulations. All of our sterility testing is performed in an isolator or clean room environments. The cell line has been screened using the membrane filtration testing methods to confirm the absence of aerobic, anaerobic and fungi microorganisms.
Genetic Stability Testing
We perform cell genetic stability studies under ICH guidelines. We can provide guidance on the appropriate testing program upon your requirements.
Application
Immunotherapy Discovery and Development
Quality Control
Cultures are screened for the presence of bacteries, yeast, fungi and mycoplasma (DNA amplification). Growth media are also certified based on U.S. Public Health Service Guidelines.
Storage
Frozen cells should be stored in a liquid nitrogen tank (-150°C~-201°C).
Handling Notes
Frozen cells should be thawed according to handling procedure or stored in a liquid nitrogen tank.
Warnings
Avoid multiple freeze/thaw cycles.
Size
1 x 10e6 cells/vial
Status
Frozen
Note
Certain products are only available in select territories. Please contact us for more information.