P450-Metric™ Cytochrome P450 2C9 (CYP2C9) ELISA Kit

CAT#: ITS-0326-YL23
Product Type: Assay Kit
Species: Human, Rat
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP2C9 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This exceptionally robust double-antibody sandwich ELISA kit guarantees the exact quantitative assessment of Cytochrome P450 2C9 across a wide variety of biological samples. Ensuring broad dynamic range and high analytical precision, this research-use-only product enables pharmacologists to thoroughly profile critical hepatic biotransformation networks. It is a fundamental analytical asset for evaluating systemic drug clearance rates and predicting complex xenobiotic interactions in rigorous preclinical ADME studies.
Features
This highly specific sandwich ELISA quantifies CYP2C9 precisely, enabling researchers to rigorously assess hepatic drug metabolism, systemic clearance, and the potential for xenobiotic interactions in vitro.
Process Relevance
Evaluating CYP2C9 to predict metabolic bottlenecks and clearance rates of weakly acidic therapeutic compounds.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Employ this quantitative sandwich ELISA to accurately measure target concentrations in tissue homogenates and relevant biological fluids.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Drug Metabolism; Pharmacokinetics; Pharmacogenomics
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.121 ng/mL
Human: 0.214 ng/mL
Species
Human, Rat
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 2C9 is a major hepatic enzyme responsible for the metabolic clearance of critical narrow-therapeutic-index drugs, such as anticoagulants and hypoglycemics. Its stringent evaluation is a mandatory requirement in ADME workflows for accurately assessing systemic clearance and potential drug-drug interactions.
For Research Use Only | Not For Clinical Use
Online Inquiry