MetaVital™ Mouse Monoamine Oxidase A (MAOA) ELISA Kit

CAT#: ITS-0326-WB65
Product Type: ELISA Kit
Species: Mouse
Target: Mouse Monoamine Oxidase A (MAOA)
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantitatively detects MAOA levels in mouse tissues, serum, plasma, and cell lysates with high specificity.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Mouse MAOA ELISA Kit provides a sensitive, reliable in vitro assay to measure Monoamine Oxidase A in mouse biological samples, enabling accurate evaluation of enzyme activity and preclinical neurochemical profiling.
Features
High detection sensitivity with a lower limit of 15 pg/mL, suitable for low-abundance MAOA measurement in diverse mouse samples.
Sandwich ELISA design ensures robust specificity by dual recognition of MAOA epitopes in complex biological matrices.
Complete kit components include pre-coated 96-well plates, biotin-labeled antibody, HRP conjugate, and TMB substrate for streamlined workflow.
Lyophilized standards maintain long-term stability, ensuring reproducible results across experiments and minimizing assay variability.
Process Relevance
Supports precise monitoring of MAOA enzyme activity for neurochemical and pharmacological studies in preclinical mouse models.
Application Stage
Preclinical research, biomarker validation, and in vitro enzymatic activity assessment.
Applications
Applicable for quantifying MAOA in mouse tissue homogenates, serum, plasma, and cell lysates, facilitating studies in neurodegeneration, psychiatric disorders, and ADME profiling studies.
Target
Mouse Monoamine Oxidase A (MAOA)
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Neuroscience, neurodegenerative disease research, pharmacokinetics (ADME), enzymology, pharmacology, biomarker discovery, oxidative stress studies, preclinical translational research, etc.
Size
96 tests
Data Output Type
Quantitative colorimetric measurement of MAOA concentrations using sandwich ELISA format.
Assay Range
78.1 pg/ml - 5000 pg/ml
LOD
46.9 pg/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
MAOA is a mitochondrial enzyme that catalyzes oxidative deamination of serotonin, norepinephrine, and dopamine. Dysregulation affects neurotransmitter balance, influencing mood disorders, aggression, and neurodegenerative progression, making MAOA a crucial preclinical biomarker.
Pathways
MAOA modulates catabolism of monoamines, generating hydrogen peroxide that influences oxidative stress pathways. It interacts with mitochondrial metabolism and neurotransmitter signaling, affecting neuronal homeostasis and synaptic function.
For Research Use Only | Not For Clinical Use
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