P450-Metric™ Cytochrome P450 1B1 (CYP1B1) ELISA Kit

CAT#: ITS-0326-YL6
Product Type: Assay Kit
Species: Human, Rat
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP1B1 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This rigorously validated double-antibody sandwich ELISA kit is developed for the precise quantitative determination of Cytochrome P450 1B1 across various research matrices. Delivering broad dynamic range and low background interference, this research-use-only assay facilitates in-depth profiling of extrahepatic xenobiotic biotransformation. It is an invaluable laboratory resource for evaluating localized tissue drug distribution, complex pro-drug activation kinetics, and unique metabolic liabilities in sophisticated ADME studies.
Features
This reliable sandwich ELISA provides precise quantification of CYP1B1, facilitating critical in vitro research on extrahepatic pro-drug activation and xenobiotic biotransformation profiles.
Process Relevance
Evaluating CYP1B1 levels to determine extrahepatic clearance and metabolic activation of targeted pro-drugs.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Utilize this quantitative sandwich ELISA to reliably measure target proteins in tissue homogenates and relevant biological fluids.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Pharmacokinetics; Drug Metabolism; Toxicology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.32 ng/mL
Human: 0.61 ng/mL
Species
Human, Rat
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 1B1 is an essential extrahepatic enzyme involved in the metabolic processing of endogenous hormones and diverse xenobiotics. Understanding its expression profile is vital for evaluating tissue-specific drug distribution and the bioactivation of therapeutic pro-drugs in complex pharmacokinetic models.
For Research Use Only | Not For Clinical Use
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