P450-Metric™ Cytochrome P450 2C18 (CYP2C18) ELISA Kit

CAT#: ITS-0326-YL9
Product Type: Assay Kit
Species: Human
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP2C18 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This highly sensitive double-antibody sandwich ELISA kit facilitates the precise quantitative detection of Cytochrome P450 2C18 in a variety of laboratory samples. Featuring remarkable intra-assay precision and rigorous target specificity, this research-use-only assay enables investigators to thoroughly examine specialized minor hepatic metabolic routes. It serves as a vital analytical instrument for assessing unique multi-enzyme xenobiotic interactions and comprehensive drug clearance in preclinical pharmacokinetics.
Features
Engineered for superior sensitivity, this sandwich ELISA allows for the accurate measurement of CYP2C18, supporting detailed investigations into specialized hepatic drug metabolism and alternative biotransformation pathways.
Process Relevance
Profiling CYP2C18 to map secondary metabolic pathways and assess extrahepatic tissue-specific drug clearance.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
This specific sandwich ELISA quantifies target concentrations across tissue homogenates, cell culture supernates, and complex biological matrices.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Drug Metabolism; Pharmacokinetics
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Human: 0.264 ng/mL
Species
Human
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Although comprising a minor fraction of the total hepatic cytochrome pool, Cytochrome P450 2C18 exhibits unique substrate specificities. Its evaluation in preclinical models aids in mapping alternative biotransformation pathways and predicting complex multi-enzyme xenobiotic interactions.
For Research Use Only | Not For Clinical Use
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