P450-Metric™ Cytochrome P450 3A2 (CYP3A2) ELISA Kit

CAT#: ITS-0326-YL25
Product Type: Assay Kit
Species: Rat
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP3A2 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This expertly developed double-antibody sandwich ELISA kit is specifically designed for the precise quantitative measurement of Cytochrome P450 3A2 in specialized experimental biological matrices. Characterized by outstanding target specificity and intra-assay reliability, this research-use-only immunoassay allows scientists to evaluate male-specific hepatic drug metabolism. It serves as a vital analytical instrument for characterizing sex-dependent pharmacokinetic differences and predicting in vivo xenobiotic interactions in robust ADME research.
Features
Delivering high-precision target detection, this sandwich ELISA accurately measures CYP3A2, providing a crucial analytical platform for evaluating sex-specific drug metabolism and preclinical pharmacokinetic variations.
Process Relevance
Quantifying CYP3A2 to profile gender-based pharmacokinetic disparities and predict specific DDI liabilities in rodents.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
This highly specific sandwich ELISA quantifies target protein concentrations across tissue homogenates, cell lysates, and biological fluids.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Preclinical Pharmacology; Drug Metabolism; Toxicology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.113 ng/mL
Species
Rat
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 3A2 is a highly significant, male-specific hepatic enzyme in preclinical rodent models that actively drives pharmaceutical clearance. Its profiling is vital in drug discovery for characterizing sex-dependent pharmacokinetic differences and establishing reliable preclinical metabolic models.
For Research Use Only | Not For Clinical Use
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