ConjugateIQ™ Total Antioxidant Capacity (T-AOC) Assay Kit

CAT#: ITS-0326-YL29
Product Type: Assay Kit
Species: All Species
Brand: ConjugateIQ™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Measures antioxidant capacity using a colorimetric method.
Brand
ConjugateIQ™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This robust colorimetric assay kit provides a comprehensive solution for quantifying total antioxidant capacity in biological research samples. By measuring the combined antioxidant defenses of a system, the kit enables researchers to effectively assess oxidative stress responses during drug-induced metabolic toxicology studies. The assay is highly reliable for evaluating how pharmaceutical treatments impact cellular redox balance, providing critical insights into potential hepatotoxicity and metabolic stress mechanisms.
Features
Robust colorimetric assay for quantifying total antioxidant capacity, enabling comprehensive assessments of drug-induced oxidative stress responses in metabolic toxicology studies.
Process Relevance
Establishing baseline redox status to support consistent evaluation of oxidative stress in metabolic toxicology studies.
Application Stage
Drug discovery, toxicology research, and safety assessment.
Applications
Evaluate cellular or systemic antioxidant status to assess oxidative stress responses during drug-induced metabolic toxicology studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Cell Culture Supernatant, Plasma, Serum, Tissue Homogenates, Whole Blood, Whole Cells
Research Areas
Toxicology; Oxidative Stress Research
Size
96 tests
Data Output Type
Absorbance (OD)
LOD
Colorimetry: 0.62 U/mL
ABTS, enzyme method: 0.047 mmol/L
FRAP method: 0.049 mmol/L
Species
All Species
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Glucuronidation by this isoform represents a major phase II detoxification pathway for bilirubin and various pharmacological agents. Alterations in its expression levels significantly impact the pharmacokinetic profile and clearance rates of therapeutic compounds.
For Research Use Only | Not For Clinical Use
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