AccuMetab™ Cynomolgus Monkey CYP2C76 Enzyme, Catalytically Active

CAT#: ITS-0426-YL45
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Cynomolgus monkey CYP2C76 for reliable preclinical Phase I profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
CYP2C76 is a unique, primate-specific isoform that has no direct functional equivalent in humans. Characterizing its metabolic activity is highly critical, as it can generate monkey-specific drug metabolites that severely confound the interpretation of preclinical toxicology data.
Key Features
Unique monkey-specific CYP isoform; Flags NHP metabolites absent in humans; Prevents misinterpretation of primate PK/PD; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Monkey
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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