AccuMetab™ Human CYP4A11 Enzyme, Catalytically Active with Cytochrome b5

CAT#: ITS-0426-YL76
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Enhanced human CYP4A11 for high-activity Phase I metabolism profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Enhancing CYP4A11 with Cytochrome b5 drives robust omega-hydroxylation activity of medium-chain fatty acids and specific xenobiotics. It provides a superior, high-turnover model for identifying unique metabolic side-reactions in lipid-targeted drug discovery.
Key Features
Cytochrome b5 supplemented for max catalytic turnover; Drives robust omega-hydroxylation of targeted lipids; Superior model for fatty-acid drug side-reactions; High-reductase expression for maximum metabolite yield
Applications
Enhanced Drug Metabolism Studies, MetID, DDI
Research Areas
ADME; Drug-Drug Interactions (DDI)
Species
Human
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
0.5 nmol; 1 nmol; 4 nmol; 10 mg
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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