P450-Metric™ Cytochrome P450 7B1 (CYP7B1) ELISA Kit

CAT#: ITS-0326-YL19
Product Type: Assay Kit
Species: Human
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP7B1 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This highly advanced double-antibody sandwich ELISA kit ensures precise quantitative determination of Cytochrome P450 7B1 levels within experimental tissue homogenates and biological fluids. Boasting excellent intra-assay precision and rigorous sensitivity, this research-use-only immunoassay enables pharmacologists to explore alternative bile acid synthesis routes. It acts as a crucial analytical resource for investigating specialized lipid-drug metabolic pathways and localized xenobiotic clearance mechanisms during comprehensive ADME research.
Features
Delivering strict analytical specificity, this quantitative ELISA accurately measures CYP7B1, providing a robust platform for investigating alternative bile acid pathways and localized xenobiotic clearance mechanisms.
Process Relevance
Assessing CYP7B1 to elucidate metabolic pathways and clearance kinetics of steroid-based neurotherapeutics.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
This sandwich ELISA accurately quantifies target enzyme concentrations in cell lysates, tissue homogenates, and other biological fluids.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Drug Metabolism; Neuropharmacology; Pharmacokinetics
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Human: 0.112 ng/mL
Species
Human
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 7B1 actively participates in the alternative bile acid synthesis pathway and the localized metabolism of neurosteroids and oxysterols. Monitoring its activity is key for researchers investigating specialized lipid-drug metabolic routes and targeted extrahepatic xenobiotic clearance.
For Research Use Only | Not For Clinical Use
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