AccuMetab™ Human UGT1A3 Enzyme, Catalytically Active

CAT#: ITS-0426-YL93
Product Type: Recombinant Phase II Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Human UGT1A3 for precise Phase II glucuronidation ADME screening.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Primarily expressed in the human liver and gastrointestinal tract, UGT1A3 catalyzes the glucuronidation of diverse compounds, including tertiary amines and bile acids. It is an essential component of comprehensive ADME panels aimed at fully mapping presystemic Phase II clearance.
Key Features
High-activity Sf9 insect cell microsome format; Evaluates GI glucuronidation of complex tertiary amines; Compatible with alamethicin for latency reduction; Requires UDPGA cofactor for assay initiation
Applications
Phase II Drug Metabolism, Glucuronidation Studies
Research Areas
ADME; Phase II Conjugation
Species
Human
Expression System
Recombinant enzymes are prepared from baculovirus-infected Sf9 insect cells.
Physical Form
Liquid
Size
2.5 mg
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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