AccuMetab™ Human SULT1A1∗ 2 Enzyme, Catalytically Active

CAT#: ITS-0426-YL87
Product Type: Recombinant Phase II Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Human SULT1A1∗ 2 for high-fidelity Phase II sulfation ADME assays.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
The SULT1A1∗ 2 allele is a highly common genetic variant associated with decreased enzymatic thermostability and altered systemic clearance rates. Testing novel compounds against this polymorphic Phase II enzyme helps researchers predict idiosyncratic drug responses in diverse patient populations.
Key Features
Prevalent genetic variant predicting idiosyncratic clearance; High-concentration E. coli cytosol format (10 mg/mL); Requires PAPS cofactor for rapid assay initiation; Essential for Phase II precision medicine screening
Applications
Phase II Drug Metabolism, Conjugation Studies
Research Areas
ADME; Phase II Conjugation
Species
Human
Expression System
Recombinant enzymes are prepared from E. coli cytosolic protein expressions.
Physical Form
Liquid
Size
1 mg
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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