P450-Metric™ Cytochrome P450 11A1 (CYP11A1) ELISA Kit

CAT#: ITS-0326-YL17
Product Type: Assay Kit
Species: Rat
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP11A1 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This strictly validated double-antibody sandwich ELISA kit guarantees the highly reliable quantitative measurement of Cytochrome P450 11A1 in targeted biological matrices. Characterized by exceptional sensitivity and optimal precision, this research-use-only product supports scientists in profiling initial mitochondrial steroidogenic pathways. It is an essential analytical platform for screening pharmacological agents against potential endocrine-disrupting properties and understanding localized xenobiotic biotransformation in advanced preclinical ADME workflows.
Features
Optimized for superior sensitivity, this double-antibody ELISA accurately quantifies CYP11A1, facilitating robust preclinical assessment of steroidogenic drug metabolism and xenobiotic-induced endocrine disruption.
Process Relevance
Profiling CYP11A1 to assess mitochondrial phase I metabolism and potential drug-induced endocrine toxicity.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Assess target protein expression across diverse tissue homogenates and cell culture supernates with this sensitive quantitative ELISA.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Toxicology; Drug Metabolism; Endocrine Pharmacology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.055 ng/mL
Species
Rat
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
As the cholesterol side-chain cleavage enzyme, Cytochrome P450 11A1 initiates the rate-limiting first step of mitochondrial steroid hormone biosynthesis. Its assessment in preclinical studies is vital for screening xenobiotics for endocrine-disrupting properties and mapping early steroidogenic drug metabolism.
For Research Use Only | Not For Clinical Use
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