AccuMetab™ Human SULT1C2 Enzyme, Catalytically Active

CAT#: ITS-0426-YL89
Product Type: Recombinant Phase II Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Human SULT1C2 for high-fidelity Phase II sulfation ADME assays.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
SULT1C2 is primarily expressed in fetal tissues and the adult kidney, contributing to the specialized Phase II clearance of specific pharmaceutical agents. It serves as a valuable tool for comprehensive ADME profiling and investigating localized renal metabolism or fetal drug exposure.
Key Features
High-concentration E. coli cytosol format (10 mg/mL); Maps localized renal metabolism and fetal exposure; Requires PAPS cofactor for rapid assay initiation; Completes whole-body Phase II clearance modeling
Applications
Phase II Drug Metabolism, Conjugation Studies
Research Areas
ADME; Phase II Conjugation
Species
Human
Expression System
Recombinant enzymes are prepared from E. coli cytosolic protein expressions.
Physical Form
Liquid
Size
1 mg
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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