P450-Metric™ Cytochrome P450 3A1 (CYP3A1) ELISA Kit

Quantifies CYP3A1 using a double-antibody sandwich ELISA.

P450-Metric™

ADME

Metabolism

This strategically formulated double-antibody sandwich ELISA kit provides highly accurate quantitative determination of Cytochrome P450 3A1 levels within specific preclinical animal models. Delivering exceptional sensitivity and rigorous analytical specificity, this research-use-only assay facilitates detailed investigation into significant hepatic xenobiotic biotransformation. It is an essential laboratory resource for scaling preclinical pharmacokinetic data and comprehensively assessing systemic drug clearance mechanisms during early-stage ADME and toxicological evaluations.

Optimized for specialized research models, this reliable sandwich ELISA quantifies CYP3A1 to facilitate critical preclinical assessments of systemic drug clearance and hepatic xenobiotic biotransformation.

Monitoring CYP3A1 in rat models to establish baseline pharmacokinetic data during early-stage in vivo screening.

Preclinical drug discovery, ADME profiling, and pharmacokinetic research

Perform reliable quantitative analysis of target expression in cell lysates and relevant biological matrices using this immunoassay.

Internal performance validation using reference standards under defined assay conditions.

Serum, plasma, tissue homogenates, cell lysates

ADME; Preclinical Pharmacology; Drug Metabolism; Toxicology

48 / 96 tests

Absorbance (OD)

Rat: 0.28 ng/mL

Rat

Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.

Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.

For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.

For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.

Shipped on ice under temperature-controlled conditions.

Cytochrome P450 3A1 serves as an essential ortholog in specific rodent models, mediating the oxidative biotransformation of a broad array of xenobiotics. Analyzing its expression is critical for accurately scaling preclinical pharmacokinetic data and evaluating xenobiotic-induced hepatic enzyme induction.