ConjugateIQ™ UDP-Glucuronosyltransferase 1A6 (UGT1A6) ELISA Kit

CAT#: ITS-0326-YL32
Product Type: Assay Kit
Species: Human, Rat, Mouse
Brand: ConjugateIQ™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies UGT1A6 protein using a sandwich ELISA method.
Brand
ConjugateIQ™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
Providing a highly sensitive solution for UGT1A6 protein detection, this sandwich ELISA kit is designed for rigorous biochemical research. It enables accurate quantification of this crucial phase II enzyme, facilitating studies on the metabolic transformation of phenolic drugs and environmental toxins. By yielding reproducible protein data, the kit supports investigators in determining metabolic stability and understanding the broader implications of glucuronidation-mediated detoxification in drug development.
Features
Highly specific UGT1A6 ELISA ensuring reliable detection of phenolic conjugation activity for improved metabolic stability profiling in drug discovery.
Process Relevance
Ensuring consistent UGT1A6 expression levels to support accurate metabolic stability profiling for phenolic substrates.
Application Stage
Drug discovery, preclinical ADME, and metabolic screening.
Applications
Quantify UGT1A6 expression in research samples to determine metabolic stability of phenolic drugs and environmental toxins.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Research Areas
ADME; Drug Metabolism
Size
96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.147 ng/mL
Human: 0.067 ng/mL
Mouse: 0.085 ng/mL
Species
Human, Rat, Mouse
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Expressed largely in extrahepatic tissues, this enzyme contributes to the first-pass metabolism of orally ingested compounds. It provides a defensive barrier by modifying reactive environmental chemicals and drug substrates before systemic circulation.
For Research Use Only | Not For Clinical Use
Online Inquiry