MetaVital™ Human Microsomal glutathione S-transferase 3 (MGST3) ELISA Kit

CAT#: ITS-0326-WB28
Product Type: ELISA Kit
Species: Rat
Target: Human Microsomal Glutathione S-Transferase 3 (MGST3) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies MGST3 concentrations in human tissue, cell lysates, and biological fluids with high sensitivity.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Human MGST3 ELISA Kit provides a robust in vitro platform for precise, quantitative measurement of MGST3 levels in tissues, cell lysates, and other biological fluids, enabling high-confidence biomarker analysis and mechanistic studies.
Features
Highly specific colorimetric detection of native MGST3 with minimal cross-reactivity across human GST isoforms.
Broad dynamic range from 0.156 to 10 ng/mL supports accurate quantification across diverse sample types.
Complete kit includes lyophilized standards and optimized reagents, reducing assay preparation time and variability.
Stability maintained with <5% activity loss under recommended storage, ensuring reproducible results across multiple experiments.
Process Relevance
Supports precise measurement of MGST3 to monitor detoxification enzyme activity in human samples.
Application Stage
Drug discovery, toxicology evaluation, and biomarker research in early- and mid-stage studies.
Applications
Enables quantitative ELISA assays in tissue homogenates, cell lysates, and biological fluids; supports mechanistic studies, pathway analyses, ADME profiling studies, and comparative biomarker investigations.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Human Microsomal Glutathione S-Transferase 3 (MGST3) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Drug metabolism, pharmacokinetics (ADME), oxidative stress biology, toxicology, cancer research, enzymology, biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative enzyme concentration measurement via colorimetric ELISA.
Assay Range
0.78 ng/ml - 50 ng/ml
LOD
< 0.442 ng/ml
Species
Rat
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
MGST3 is a microsomal glutathione S-transferase critical for detoxifying reactive oxygen species and xenobiotics in human cells. Its activity reflects cellular oxidative stress responses, making it a valuable biomarker in pharmacology and toxicology studies.
Pathways
MGST3 participates in the glutathione-mediated detoxification pathway, linking oxidative stress signals to cellular protection mechanisms. It interacts upstream with reactive electrophiles and downstream with conjugated metabolites for excretion.
For Research Use Only | Not For Clinical Use
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