MetaVital™ Rat Glutathione S-transferase alpha-4 (GSTA4) ELISA Kit

CAT#: ITS-0326-WB27
Product Type: ELISA Kit
Species: Rat
Target: Rat Glutathione S-transferase alpha-4 (GSTA4) protein
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies GSTA4 protein levels in rat biological samples for oxidative stress and detoxification research.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Rat Glutathione S-transferase alpha-4 (GSTA4) ELISA Kit provides a robust in vitro platform to accurately measure GSTA4 concentrations in rat serum, plasma, tissue lysates, and cell culture supernatants, supporting pharmacological, toxicological, and oxidative stress studies.
Features
High sensitivity enables precise detection of rat GSTA4 protein across a broad dynamic range, supporting low-abundance sample analysis.
Excellent specificity ensures minimal cross-reactivity with other GST isoforms or homologous proteins, maintaining accurate quantification.
Complete kit includes lyophilized standards and ready-to-use reagents, facilitating reproducible results with minimal assay preparation.
Optimized storage and reagent stability provide consistent performance over extended periods, enabling reliable preclinical research workflows.
Process Relevance
Supports monitoring of GSTA4 activity to evaluate detoxification capacity and oxidative stress responses in experimental rat models.
Application Stage
EPreclinical drug discovery, mechanistic studies, and in-process biomarker quantification in oxidative stress or toxicity research.
Applications
Ideal for ELISA-based quantification of GSTA4 in serum, plasma, tissue homogenates, or cell culture supernatants for ADME profiling studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Rat Glutathione S-transferase alpha-4 (GSTA4) protein
Detection Method
Colorimetric
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Assay Measures
Quantitative
Research Areas
Oxidative stress research, toxicology, pharmacokinetics (ADME), cancer biology, enzymology, preclinical biomarker studies, etc.
Size
96 tests
Data Output Type
Quantitative colorimetric measurement of GSTA4 protein levels using an endpoint ELISA assay.
Assay Range
0.78 ng/ml - 50 ng/ml
LOD
< 0.442 ng/ml
Species
Rat
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
GSTA4 is a cytosolic enzyme involved in conjugating glutathione to lipid peroxidation products, protecting cells from oxidative damage. Its activity is central in studies of redox biology, chemical toxicity, and metabolic stress in preclinical models.
Pathways
GSTA4 participates in phase II detoxification, catalyzing glutathione conjugation of reactive aldehydes and electrophilic compounds. Upstream oxidative stress signals induce expression, while downstream conjugates facilitate cellular clearance, maintaining redox homeostasis.
For Research Use Only | Not For Clinical Use
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