P450-Metric™ Cytochrome P450 1A2 (CYP1A2) ELISA Kit

CAT#: ITS-0326-YL4
Product Type: Assay Kit
Species: Human, Rat, Mouse
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP1A2 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This premium double-antibody sandwich ELISA kit is purposefully engineered for the exact quantitative measurement of Cytochrome P450 1A2 in experimental biological fluids and tissue homogenates. Ensuring excellent intra-assay precision, this research-use-only product allows pharmacologists to confidently analyze hepatic xenobiotic clearance mechanisms. It provides a highly reliable analytical foundation for determining potential drug-drug interactions and modeling systemic drug metabolism within comprehensive preclinical ADME research.
Features
Engineered for high analytical sensitivity, this sandwich ELISA accurately quantifies CYP1A2 expression, enabling critical evaluation of hepatic xenobiotic clearance and potential drug-drug interactions in preclinical assays.
Process Relevance
Assessing CYP1A2 activity to predict clearance of aromatic compounds and manage severe drug-drug interactions.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Perform quantitative analysis of target expression in cell lysates and relevant biological matrices using this specific immunoassay.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Drug Metabolism; Pharmacokinetics; Toxicology
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Rat: 0.55 ng/mL
Human: 0.31 ng/mL
Mouse: 0.125 ng/mL
Species
Human, Rat, Mouse
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 1A2 is a major hepatic enzyme responsible for the oxidative clearance of a wide array of pharmaceuticals and environmental polycyclic aromatic hydrocarbons. Monitoring its induction or inhibition is indispensable for predicting systemic drug bioavailability and modeling xenobiotic drug-drug interactions.
For Research Use Only | Not For Clinical Use
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