P450-Metric™ Cytochrome P450 2C19 (CYP2C19) ELISA Kit

Quantifies CYP2C19 using a double-antibody sandwich ELISA.

P450-Metric™

ADME

Metabolism

This highly sensitive double-antibody sandwich ELISA kit enables the exceptionally precise quantitative detection of Cytochrome P450 2C19 across diverse laboratory samples. Offering superior analytical precision and rigorous reproducibility, this research-use-only platform supports investigators in mapping highly polymorphic xenobiotic clearance pathways. It represents a critically important analytical tool for evaluating systemic drug disposition and identifying significant metabolic liabilities during advanced preclinical pharmacokinetic and ADME profiling workflows.

This precision-engineered sandwich ELISA delivers highly specific quantification of CYP2C19, enabling detailed in vitro investigations into drug clearance pathways and polymorphic xenobiotic metabolism for ADME profiling.

Assessing CYP2C19 to investigate variable drug metabolism profiles and detailed DDI risks for promising xenobiotics.

Preclinical drug discovery, ADME profiling, and pharmacokinetic research

Employ this reliable sandwich ELISA to accurately measure target enzyme concentrations in tissue homogenates and biological fluids.

Internal performance validation using reference standards under defined assay conditions.

Serum, plasma, tissue homogenates, cell lysates

ADME; Drug Metabolism; Pharmacokinetics; Pharmacogenomics

48 / 96 tests

Absorbance (OD)

Human: 0.125 ng/mL

Human

Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.

Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.

For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.

For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.

Shipped on ice under temperature-controlled conditions.

Cytochrome P450 2C19 is a critical hepatic enzyme that mediates the metabolism of heavily prescribed therapeutics, including antiplatelet agents and proton pump inhibitors. Because of its distinct genetic polymorphisms, evaluating its activity is essential for predicting metabolic clearance rates and characterizing polymorphic drug disposition.