P450-Metric™ Cytochrome P450 3A7 (CYP3A7) ELISA Kit

CAT#: ITS-0326-YL22
Product Type: Assay Kit
Species: Human
Brand: P450-Metric™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies CYP3A7 using a double-antibody sandwich ELISA.
Brand
P450-Metric™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
This highly reliable double-antibody sandwich ELISA kit offers precise quantitative detection of Cytochrome P450 3A7 expression in experimental fetal tissue homogenates and lysates. Featuring superior analytical reproducibility and exact specificity, this research-use-only immunoassay helps investigators elucidate early developmental xenobiotic metabolism. It operates as an invaluable laboratory tool for modeling pediatric pharmacokinetic profiles and assessing fetal drug exposure pathways within specialized preclinical ADME research protocols.
Features
Providing high-sensitivity target quantification, this robust ELISA accurately measures CYP3A7, an indispensable tool for investigating fetal drug metabolism and pediatric pharmacokinetic profiles in early-stage research.
Process Relevance
Profiling CYP3A7 to model maternal-fetal drug transfer and pediatric pharmacokinetic clearance during early development.
Application Stage
Preclinical drug discovery, ADME profiling, and pharmacokinetic research
Applications
Measure target enzyme expression in cell lysates, tissue homogenates, and complex biological fluids utilizing this precise assay.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Sample Type
Serum, plasma, tissue homogenates, cell lysates
Research Areas
ADME; Developmental Pharmacology; Drug Metabolism; Pharmacokinetics
Size
48 / 96 tests
Data Output Type
Absorbance (OD)
LOD
Human: 0.27 ng/mL
Species
Human
Storage
Upon receipt, please follow the storage recommendations in the USER MANUAL to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. Do not store at elevated temperatures for extended periods.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Cytochrome P450 3A7 is the predominant metabolic enzyme expressed within the fetal liver, driving the early developmental metabolism of endogenous compounds. For developmental pharmacology, its analysis is fundamental for predicting transplacental xenobiotic metabolism and modeling pediatric pharmacokinetic profiles.
For Research Use Only | Not For Clinical Use
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