AccuMetab™ Rat CYP3A9 Enzyme, Catalytically Active
CAT#: ITS-0426-YL57
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Rat CYP3A9 for reliable preclinical Phase I ADME profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
Rat CYP3A9 is a sex-specific Phase I enzyme that plays a critical role in the hepatic clearance of xenobiotics in male rats. Its unique expression profile makes it indispensable for interpreting the sex-dependent pharmacokinetic differences frequently observed in early rodent safety trials.
Key Features
Male-specific rat Phase I enzyme; De-convolutes sex-based rodent PK differences; Pre-coupled with rat NADPH reductase; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Rat
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.