MetaVital™ Mouse Glutathione S Transferase Mu 1 (GSTm1) ELISA Kit

CAT#: ITS-0326-WB37
Product Type: ELISA Kit
Species: Mouse
Target: Mouse Glutathione S-transferase Mu 1 (GSTm1)
Brand: MetaVital™
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Quantifies GSTm1 protein levels in mouse tissues, cell lysates, and biological fluids using ELISA methodology.
Brand
MetaVital™
Development Stage
ADME
ADME Research Domain
Metabolism
Description
MetaVital™ Mouse GSTm1 ELISA Kit provides a high-sensitivity, in vitro solution for precise quantification of Glutathione S-transferase Mu 1 in mouse biological samples. Ideal for preclinical research, toxicology studies, and enzymatic activity profiling, this kit ensures reproducible measurements across multiple sample types.
Features
High specificity for mouse GSTm1 ensures accurate detection without cross-reactivity from other GST isoforms in complex matrices.
Colorimetric ELISA format provides a broad detection range for sensitive, quantitative protein measurement from 0.2-10 ng/mL.
Optimized reagent stability under recommended storage maintains assay consistency and reproducibility over multiple experimental runs.
Complete kit for 96 tests with all components included, supporting efficient, standardized workflow for preclinical studies.
Process Relevance
Supports precise monitoring of GSTm1 expression to assess enzymatic detoxification, oxidative stress, and hepatotoxicity in preclinical studies.
Application Stage
Drug discovery, toxicological evaluation, and enzymatic biomarker analysis in preclinical development.
Applications
Designed for quantitative ELISA detection of GSTm1 in tissue homogenates, cell lysates, serum, and plasma for downstream ADME profiling studies.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Target
Mouse Glutathione S-transferase Mu 1 (GSTm1)
Detection Method
Colorimetric
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Assay Measures
Quantitative
Research Areas
Enzymology, pharmacokinetics (ADME), pharmacology, toxicology, oxidative stress research, preclinical biomarker discovery, etc.
Size
96 tests
Data Output Type
Quantitative colorimetric measurement of GSTm1 protein concentration in biological samples.
Assay Range
1.56 ng/ml - 100 ng/ml
LOD
< 0.58 ng/ml
Species
Mouse
Assay Measures
Quantitative
Storage
Upon receipt, store the kit in accordance with the storage conditions specified in the product manual.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to -20°C; storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
12 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
GSTm1 is a critical detoxification enzyme in the glutathione S-transferase Mu family, mediating conjugation of glutathione to electrophilic compounds. Its expression reflects cellular response to oxidative stress, xenobiotic metabolism, and liver function in mice.
Pathways
GSTm1 participates in glutathione-dependent detoxification pathways, modulating reactive oxygen species and xenobiotic metabolism. It interacts upstream with oxidative stress sensors and downstream with phase II conjugation processes.
For Research Use Only | Not For Clinical Use
Online Inquiry