PARP-targeted RNA Modification and Metabolomics Analysis Tool

CAT#: ITS-0524-CR256
Cell Type: M1 macrophages
RNA writers: METTL3
RNA readers: YTHDC1
RNA erasers: ALKBH5
Enzymes: MDH1
RNA types: mRNAs
Modification: ψ
RNA editing: T to C
Short Description
This product is a PARP-targeted RNA modification and metabolomics analysis tool based on the ψ (METTL3-YTHDC1-ALKBH5-MDH1-Cholesterol) modification and Glycolysis-mediated (CPEB4-SAM-ADP) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDC1
RNA erasers
ALKBH5
Enzymes
MDH1
RNA types
mRNAs
Modification
ψ
Label
Cholesterol
RNA editing
T to C
Cell Type
M1 macrophages
Oligonucleotide
cET, 2'-MOE
RNA Construction
mRNAs-ψ-METTL3-YTHDC1-ALKBH5-MDH1-Cholesterol
Substrates
SAM
Cofactors
ADP
Pathway
Glycolysis
Epigenetic regulator
P300/CBP overexpression
Metabolic alteration
Upregulating glycolysis and amino acidsmetabolism
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
CPEB4
Metabolic Reprogramming
Glycolysis-CPEB4-SAM-ADP
Target
PARP
Alternative Names
Poly (ADP-ribose) polymerase (PARP
Format
Liquid
Shipping
All ordered products are shipped from Fedex or UPS.
Handling Advice
Prevent prolonged exposure to light.
Storage
Recommended long-term storage in - 20 ° C, to ensure the longest shelf life of products.
For Research Use Only | Not For Clinical Use
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