AccuMetab™ Cynomolgus Monkey CYP2C8 Enzyme, Catalytically Active

CAT#: ITS-0426-YL42
Product Type: Recombinant Phase I Metabolizing Enzyme
Brand: AccuMetab
Development Stage: ADME
ADME Research Domain: Metabolism
Short Description
Cynomolgus monkey CYP2C8 for reliable preclinical Phase I profiling.
Brand
AccuMetab
Development Stage
ADME
ADME Research Domain
Metabolism
Background
This non-human primate ortholog closely mimics human CYP2C8 in the clearance of large, complex therapeutic molecules. It is an indispensable in vitro tool for validating the cynomolgus monkey as a predictive preclinical model for specific drug-drug interactions.
Key Features
Authentic non-human primate ortholog; Validates cyno models for large-molecule drugs; Pre-coupled with monkey NADPH reductase; Supplied in controlled, low-reductase formats
Applications
Drug Metabolism Studies, Preclinical Species Comparison
Research Areas
ADME; Preclinical Toxicology
Species
Monkey
Expression System
Recombinant enzymes prepared from E. coli and co-expressed with NADPH CYP-reductase.
Physical Form
Liquid
Size
1 nmol
Storage
-80°C
Storage Comment
When stored at -80°C, our product remains stable and retains full functional activity for up to 10 years.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Our enzyme products are shipped at -80°C.
For Research Use Only | Not For Clinical Use
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