GlycoErase™ ST3GAL6 Knockout CHO-K1 Cell Line (CAT#: GLJF-0425-JF91)

Description	The ST3GAL6 knockout CHO-K1 cell line, successfully constructed without ST3 beta-galactoside alpha-2,3-sialyltransferase 6, preliminary cell glycobiology analysis indicates that this cell line may cause a significant decrease in the overall sialylation modification capability within CHO cells, ST3GAL6 protein, as an important member of the sialic acid transferase family, directly participates in catalyzing sialic acid transfer reactions, this CHO knockout cell line model will provide strong support for comprehensively and systematically analyzing the sialylation regulation network in CHO biomanufacturing cells.
Product Type	KO Cell Lines
Species	Hamster
Cell Morphology	Epithelial, adherent
Passage Ratio	1:3~1:5
Cell Line	CHO-K1
Lineage	Chinese hamster ovary

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	2 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	ST3GAL6
Full Name	ST3 Beta-galactoside alpha-2,3-sialyltransferase 6
Alternative Name	ST3GALVI, SIAT10
Location	3q12.1
Gene ID	10402
Summary	Transfers sialic acid to terminal positions on glycolipids and glycoproteins, contributing to the diversity and function of cell surface molecules.