GlycoErase™ ST6GALNAC1 Knockout CHO-K1 Cell Line (CAT#: GLJF-0425-JF94)

Description	The ST6GALNAC1 knockout CHO-K1 cell line, successfully prepared without ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, cell biology research shows that this cell line may significantly disrupt the normal sialylation modification pattern of endogenous glycoproteins and glycolipids in CHO cells, ST6GALNAC1 protein knockout may significantly affect cell-cell recognition and adhesion, signal transduction between cells and extracellular matrix, as well as important physiological functions of multiple key biomolecules within CHO cells.
Product Type	KO Cell Lines
Species	Hamster
Cell Morphology	Epithelial, adherent
Passage Ratio	1:3~1:5
Cell Line	CHO-K1
Lineage	Chinese hamster ovary

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	ST6GALNAC1
Full Name	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Alternative Name	SIAT7A, ST6GalNAcI
Location	17q25.1
Gene ID	55808
Summary	Transfers sialic acid to O-linked GalNAc residues, forming the cancer-associated sialyl-Tn antigen and affecting cell-cell interactions.