GlycoErase™ ST6GALNAC4 Knockout Human Glioma Cell A172 (CAT#: GLJF-0525-JF865)

Description	The ST6GALNAC4 knockout A172 cell line, lacking ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved in modulating cell-cell interactions, enables the study of cell-cell interaction disruption in glioma, potentially affecting cell adhesion mechanisms, intercellular communication pathways, and the sialylation of cell surface proteins relevant to the tumor microenvironment.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:3
Cell Line	A172
Primary Disease	Diffuse Glioma
Lineage	CNS/Brain

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	DMEM & FBS & Glutamine
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	ST6GALNAC4
Full Name	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
Alternative Name	SIAT7D, SIAT3C, ST6GALNACIV
Location	9q34.11
Gene ID	27090
Summary	Sialyltransferase with restricted substrate specificity, preferring glycoproteins and involved in the synthesis of ganglioside GD1A from GM1B.