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GlycoFlux™ Human PPP1R9B Overexpression HEK293T Cell Line (CAT#: GLJF-0925-JF583)

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1 M cells/vial*2

Description GlycoFlux™ human PPP1R9B overexpression HEK293T cell line is a stable glycoengineered line that constitutively overexpresses spinophilin (PPP1R9B), a PP1 scaffold enriched at dendritic spines with putative tumor suppressor roles. It enables analysis of how localized phosphatase signaling regulates glycosyltransferase compartmentalization, receptor glycoforms, and endocytosis/recycling kinetics.
Product Type Overexpression Cell Lines
Species Human
Cell Morphology Epithelial-like, adherent
Passage Ratio 1:2~1:4
Cell Line HEK293T
Lineage Embryonic kidney
Cell Viability >90%
Sterility Test The sterility test indicated an absence of microbial growth.
Identity Test STR identification
Mycoplasma Test Negative
Virus Test Negative for HIV, HBV and HCV.
Genetic Stability Testing We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation qPCR, Sanger Sequencing
Culture Medium DMEM & FBS & Penicillin/Streptomycin
Application Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays.
Size 1 M cells/vial*2
Product Format Frozen
Shipping Dry ice
Availability Status Made to order
Handling Notes Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.
Target PPP1R9B
Full Name Protein Phosphatase 1 Regulatory Subunit 9B
Alternative Name Spn; SPINO; PPP1R6; PPP1R9
Location 17q21.33
Gene ID 84687
Summary Encodes a scaffold protein acting as a protein phosphatase 1a regulator, enriched in dendritic spines and possibly functioning as a tumor suppressor with reduced expression in certain cancers.
For Research Use Only.
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