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The quantitative human γABRα2 (glycosylated) sandwich ELISA kit is designed to detect human γ-aminobutyric acid A receptor α2 (γABRα2) levels. GABRA2 is a subunit of the GABA A receptor. GABA is the primary inhibitory neurotransmitter in the brain. GABRA2 contributes to the formation of GABA A receptors. These receptors mediate inhibitory synaptic transmission, which is crucial for regulating neuronal excitability. The kit is suitable for various biological samples such as tissue homogenates. Its sensitivity is 0.069 ng/mL, which can accurately detect low concentrations of γABRα2 in the sample.
The quantitative human γABRα2 (glycosylated) sandwich ELISA kit is used to measure glycosylated GABRA2 levels in samples. This measurement is important in neuroscience research, especially for studying GABAergic signaling and neurological disorders. The kit is applied in investigations of conditions such as anxiety, epilepsy, and alcohol dependence, where GABRA2 expression may be altered.