Quantitative Human CES2 (Glycosylated) Sandwich ELISA Kit

The quantitative human CES2 (glycosylated) sandwich ELISA kit is designed to detect human carboxylesterase 2 (CES2) levels. CES2 is an enzyme that hydrolyzes various esters, including drugs and endogenous compounds, playing a significant role in drug metabolism and lipid homeostasis. It contributes to the detoxification and processing of xenobiotics and endogenous substrates. The kit is suitable for various biological samples such as tissue homogenates, serum, plasma. Its sensitivity is 0.125 ng/mL, which can accurately detect low concentrations of CES2 in the sample.

CES2

Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution

Tissue homogenates, serum, plasma

100 μL

0.125 ng/mL

Quantitative sandwich ELISA

1 ng/mL-10 ng/mL

1 h-5 h

450 nm

Store at 2-8°C for long term storage.

Human

Carboxylesterase 2

CES2; Carboxylesterase 2; CE-2; CES2A1; Methylumbelliferyl-acetate deacetylase 2

111, 276

The quantitative human CES2 (glycosylated) sandwich ELISA kit is useful for researchers studying drug metabolism, pharmacokinetics, and lipid-related disorders, where CES2 activity is crucial. By quantifying CES2, researchers can gain insights into its role in drug disposition and disease pathogenesis, and explore potential therapeutic interventions related to enzyme modulation.

Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;

Serum sample: n=5, 80-95%;
Plasma sample: n=4, 90-105%;

The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.