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| Size | Qty | Add To Basket |
|---|---|---|
| 1×48 T | ||
| 1×96 T |
| Product Description | The quantitative human DNM1L (glycosylated) sandwich ELISA kit is designed to detect human dynamin 1 like protein (DNM1L) levels. DNM1L is a GTPase involved in mitochondrial fission, a process essential for mitochondrial dynamics and cellular function. It plays a critical role in regulating mitochondrial morphology and distribution. The kit is suitable for various biological samples such as tissue homogenates, cell lysates. Its sensitivity is 0.082 ng/mL, which can accurately detect low concentrations of DNM1L in the sample. |
| Target | DNM1L |
| O-Glycosylation Site | 585, 586 |
| Sample Types | Tissue homogenates, cell lysates |
| Sample Volume | 100 μL |
| Sensitivity | 0.082 ng/mL |
| Detection Principle | Quantitative sandwich ELISA |
| Detection Range | 1 ng/mL-10 ng/mL |
| Detection Time | 1 h-5 h |
| Detection Wavelength | 450 nm |
| Storage | Store at 2-8°C for long term storage. |
| Species | Human |
| Full Name | Dynamin 1 like protein |
| Alternate Names | DNM1L; Dynamin 1 like protein; DRP1; DLP1; Dynamin-related protein 1 |
| Uniprot No. | O00429 |
| Application | The quantitative human DNM1L (glycosylated) sandwich ELISA kit is valuable for researchers investigating mitochondrial dysfunction in neurodegenerative diseases, cancer, and metabolic disorders, where DNM1L activity is often altered. By quantifying DNM1L, researchers can gain insights into the role of mitochondrial dynamics in disease pathogenesis and explore potential therapeutic targets. |
| Kit Components | Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution |
| Precision | Intra-Assay: n=20, CV <8%; Inter-Assay: n=20, CV <10%; |
| Recovery | Serum sample: n=5, 90-110%; Plasma sample: n=4, 85-100%; |
| Standard Curve | ![]() The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested. |