Quantitative Human PIGR (Glycosylated) Sandwich ELISA Kit (CAT#: GLJF-0525-HX138)

Product Description	The quantitative human PIGR (glycosylated) sandwich ELISA kit is designed to detect human polymeric immunoglobulin receptor (PIGR) levels. PIGR is a transmembrane protein that mediates the transcytosis of polymeric immunoglobulins, primarily IgA, across epithelial cells. It's crucial for mucosal immunity, delivering IgA to mucosal surfaces for defense against pathogens. The kit is suitable for various biological samples such as serum, plasma, urine. Its sensitivity is 27.283 pg/mL, which can accurately detect low concentrations of PIGR in the sample.
Target	PIGR
N-Glycosylation Site	83, 90, 135, 186, 421, 469, 499
Sample Types	Serum, plasma, urine
Sample Volume	100 μL
Sensitivity	27.283 pg/mL
Detection Principle	Quantitative sandwich ELISA
Detection Range	65 pg/mL-3500 pg/mL
Detection Time	1 h-5 h
Detection Wavelength	450 nm
Storage	Store at 2-8°C for long term storage.

Species	Human
Full Name	Polymeric immunoglobulin receptor
Alternate Names	PIGR; Polymeric immunoglobulin receptor; SC; Secretory component
Uniprot No.	P01833

Application	The quantitative human PIGR (glycosylated) sandwich ELISA kit is valuable in research investigating mucosal immunity, inflammatory bowel disease, and other conditions involving epithelial transport of IgA. Researchers utilize this ELISA to quantify PIGR levels, providing insights into its role in mucosal defense and related pathologies.
Kit Components	Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution
Precision	Intra-Assay: n=20, CV <8%; Inter-Assay: n=20, CV <10%;
Recovery	Serum sample: n=5, 80-95%; Plasma sample: n=4, 90-110%;
Standard Curve	The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.