Quantitative Human PIGR (Glycosylated) Sandwich ELISA Kit

The quantitative human PIGR (glycosylated) sandwich ELISA kit is designed to detect human polymeric immunoglobulin receptor (PIGR) levels. PIGR is a transmembrane protein that mediates the transcytosis of polymeric immunoglobulins, primarily IgA, across epithelial cells. It's crucial for mucosal immunity, delivering IgA to mucosal surfaces for defense against pathogens. The kit is suitable for various biological samples such as serum, plasma, urine. Its sensitivity is 27.283 pg/mL, which can accurately detect low concentrations of PIGR in the sample.

PIGR

Pre-coated ELISA plate; Lyophilized standard; Biotin-labeled antibody; HRP-avidin; Various diluents; Wash buffer; TMB chromogenic substrate; Stop solution

Serum, plasma, urine

100 μL

27.283 pg/mL

Quantitative sandwich ELISA

65 pg/mL-3500 pg/mL

1 h-5 h

450 nm

Store at 2-8°C for long term storage.

Human

Polymeric immunoglobulin receptor

PIGR; Polymeric immunoglobulin receptor; SC; Secretory component

83, 90, 135, 186, 421, 469, 499

The quantitative human PIGR (glycosylated) sandwich ELISA kit is valuable in research investigating mucosal immunity, inflammatory bowel disease, and other conditions involving epithelial transport of IgA. Researchers utilize this ELISA to quantify PIGR levels, providing insights into its role in mucosal defense and related pathologies.

Intra-Assay: n=20, CV <8%;
Inter-Assay: n=20, CV <10%;

Serum sample: n=5, 80-95%;
Plasma sample: n=4, 90-110%;

The standard curve is for reference only, and a new standard curve should be generated for each set of samples tested.