Recombinant Human ANGPTL4 Protein, Glycoengineered Human Cell Lines (CAT#: GLJF-0622-JF252)

Product Overview	Recombinant human ANGPTL4 protein (NP_001034756.1) is produced in Glycoengineered Human Cell Lines. This expression system is used for the production of glycoproteins and antibodies with human post-translational modifications.
Source	Glycoengineered Human Cell Lines
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	ANGPTL4
Full Name	Angiopoietin-related protein 4
Gene ID	51129
Uniprot ID	Q9BY76
Accession Number	NP_001034756.1
Background	This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
Alternate Names	Angiopoietin-like protein 4; Hepatic fibrinogen/angiopoietin-related protein; HFARP [Cleaved into: ANGPTL4 N-terminal chain; ANGPTL4 C-terminal chain]; ANGPTL4; ARP4; HFARP; PGAR; PP1158; PSEC0166; UNQ171/PRO197