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Recombinant Human Integrin subunit alpha 2b, Wheat germ (CAT#: GP05-194J)

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Product Overview Recombinant Human Integrin subunit alpha 2b (NP_000410.2) was produced using Wheat germ cell-free expression system. Measured by its binding ability in a functional ELISA.
Biological Activity Measured by its binding ability in a functional ELISA.
Source Wheat germ cell-free expression system
Species Human
Purity >90%, determined by SDS-PAGE.
Conjugation Unconjugated
Target ITGA2B
Full Name Integrin subunit alpha 2b
Gene ID 3674
Uniprot ID P08514
Accession Number NP_000410.2
Background This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia.
Alternate Names GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93
For Research Use Only.
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