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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human GALNT10 overexpression glycoengineered cell is a stable cell line that constitutively overexpresses GALNT10, initiating mucin-type O-glycans by transferring GalNAc from UDP-GalNAc to polypeptide acceptors. The platform enables peptide-selective initiation mapping, control of mucin-like spacer properties, and fine-tuning of cell-surface shielding or receptor engagement. |
| Product Type | Overexpression Cell Lines |
| Cell Line | As requested by the client. |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | GALNT10 |
| Full Name | Polypeptide N-acetylgalactosaminyltransferase 10 |
| Alternative Name | GalNAc-T10 |
| Location | 5q33.2 |
| Gene ID | 55568 |
| Summary | Catalyzes the first step in mucin-type oligosaccharide synthesis by transferring GalNAc from UDP-GalNAc to polypeptide acceptors. |