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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human PPP1R3G overexpression Raji cell line is a stable cell line engineered to overexpress PPP1R3G, a predicted PP1 regulatory subunit with glycogen-binding activity. It regulates glycogen synthesis and is involved in glucose homeostasis. This model enables exploration of glycogen-targeted PP1 complexes and metabolic regulation. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Lymphoblast-like, suspension growth |
| Passage Ratio | 1:2~1:4 |
| Cell Line | Raji |
| Primary Disease | Burkitt's lymphoma |
| Lineage | B lymphocyte (B cell) |
| Lineage Subtype | Mature B cell, widely used in EBV-related studies |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | FBS & RPMI |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | PPP1R3G |
| Full Name | Protein Phosphatase 1 Regulatory Subunit 3G |
| Location | 6p25.1 |
| Gene ID | 648791 |
| Summary | Predicted to enable glycogen binding activity and protein phosphatase 1 binding activity. Predicted to be involved in regulation of glycogen biosynthetic process. Predicted to act upstream of or within glucose homeostasis; positive regulation of glycogen (starch) synthase activity; and positive regulation of glycogen biosynthetic process. Predicted to be located in cytoplasm. Predicted to be part of protein phosphatase type 1 complex. |