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Recombinant Human herpesvirus 5 (HHV-5) (strain Merlin) Envelope glycoprotein L (gL) (31-278 aa) [6xHis-tag], Yeast

CAT#: GPX04-203J

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Specifications
Product Overview
Recombinant Human herpesvirus 5 (HHV-5) (strain Merlin) Envelope glycoprotein L (31-278 aa) was expressed in Yeast with a 6xHis-tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
Yeast
Species
Human herpesvirus 5 (HHV-5) (strain Merlin)
Fragment
31-278 aa
Sequence
AAVSVAPTAAEKVPAECPELTRRCLLGEVFEGDKYESWLRPLVNVTGRDGPLSQLIRYRPVTPEAANSVLLDEAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
Tag
6xHis-tag at the N-terminus
Predicted MW
29.5 kDa
Purity
>90%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
gL
Full Name
Envelope glycoprotein L
Gene ID
Uniprot ID
Background
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
Alternate Names
Envelope glycoprotein L
For Research Use Only.
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