Recombinant CD28 Protein (Asn 20-Lys 149) [His] (VAng-1243Lsx)

Mouse CD28, His tag, is expressed in HEK 293 cells. (Uniprot ID: P31041-1)

Datasheet

Specifications

Source

HEK293 Cells.

Target

CD28

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive (expression is independent of environmental factors).

Alternative Names

CD28, Tp44