GlycoErase™ TRIM7 Knockout HEK293 Cell Line (CAT#: GLJF-0825-JF487)

Description	GlycoErase™ TRIM7 knockout HEK293 cell line is a HEK293 model lacking TRIM7 expression. TRIM7 encodes an E3 ubiquitin ligase of the tripartite motif family, implicated in glycogen synthesis initiation and innate immune regulation. This knockout provides a human-based system to analyze ubiquitin-mediated control of glycogen biogenesis, TRIM-family functions, and metabolism-immunity crosstalk, supporting cancer, metabolic, and virology research.
Product Type	KO Cell Lines
Species	Human
Cell Morphology	Epithelial-like, adherent
Passage Ratio	1:2~1:4
Cell Line	HEK293
Lineage	Embryonic kidney

Cell Viability	>90%
Sterility Test	The sterility test indicated an absence of microbial growth.
Identity Test	STR identification
Mycoplasma Test	Negative
Virus Test	Negative for HIV, HBV and HCV.
Genetic Stability Testing	We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements.
Validation	PCR, Sanger Sequencing
Culture Medium	FBS & Penicillin/Streptomycin & Proline & RPMI
Application	Functional assay
Size	1 M cells/vial*2
Product Format	Frozen
Shipping	Dry ice
Availability Status	Made to order
Handling Notes	Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to.
Product Disclaimer	This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous.

Target	TRIM7
Full Name	Tripartite Motif Containing 7
Alternative Name	GNIP; RNF90
Location	5q35.3
Gene ID	81786
Summary	The encoded protein is a TRIM family member with RING, B-box types 1 and 2, and a coiled-coil region, found in both nucleus and cytoplasm, potentially involved in glycogen synthesis initiation. Multiple isoforms exist.