There is no product in the shopping cart, buy it!
| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human TRIM7 overexpression HEK293T cell line is a stable cell line expressing TRIM7, a RING-type E3 ubiquitin ligase of the TRIM family with B-box and coiled-coil domains. Present in both cytoplasm and nucleus, TRIM7 influences glycogen synthesis initiation and innate immunity. This engineered model enables studies of ubiquitination pathways, glycogen regulation, and host defense against viral infection. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Epithelial-like, adherent |
| Passage Ratio | 1:2~1:4 |
| Cell Line | HEK293T |
| Lineage | Embryonic kidney |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | DMEM & FBS & Penicillin/Streptomycin |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | TRIM7 |
| Full Name | Tripartite Motif Containing 7 |
| Alternative Name | GNIP; RNF90 |
| Location | 5q35.3 |
| Gene ID | 81786 |
| Summary | The encoded protein is part of the TRIM family, featuring a RING domain, two B-box domains, and a coiled-coil structure. It is localized to nucleus and cytoplasm and may contribute to initiating glycogen synthesis. |