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| Size | Qty | Add To Basket |
|---|---|---|
| 1 M cells/vial*2 |
| Description | GlycoFlux™ human ST6GALNAC1 overexpression Raji cell line is a stable cell line engineered to overexpress ST6GALNAC1, a sialyltransferase that modifiesO-linked GalNAc residues to generate the cancer-associated sialyl-Tn antigen. This model is widely applicable in tumor immunology, glycan biomarker discovery, and studies of altered cell-cell interactions in malignancies. |
| Product Type | Overexpression Cell Lines |
| Species | Human |
| Cell Morphology | Lymphoblast-like, suspension growth |
| Passage Ratio | 1:2~1:4 |
| Cell Line | Raji |
| Primary Disease | Burkitt's lymphoma |
| Lineage | B lymphocyte (B cell) |
| Lineage Subtype | Mature B cell, widely used in EBV-related studies |
| Cell Viability | >90% |
| Sterility Test | The sterility test indicated an absence of microbial growth. |
| Identity Test | STR identification |
| Mycoplasma Test | Negative |
| Virus Test | Negative for HIV, HBV and HCV. |
| Genetic Stability Testing | We conduct cell genetic stability studies in full compliance with ICH guidelines. Our expertise enables us to design and execute a comprehensive testing program tailored to your specific needs and regulatory requirements. |
| Validation | qPCR, Sanger Sequencing |
| Culture Medium | FBS & RPMI |
| Application | Mechanistic studies; Exploration of glycosylation and signaling pathways in cancer, metabolic, and immune-related diseases; Drug target validation and other functional assays. |
| Size | 1 M cells/vial*2 |
| Product Format | Frozen |
| Shipping | Dry ice |
| Availability Status | Made to order |
| Handling Notes | Upon receipt, this product must be immediately transferred from dry ice to liquid nitrogen (-150°C to -190°C) and stored in a liquid nitrogen tank. Cell viability is critically dependent on proper handling. We cannot guarantee viability if these instructions are not strictly adhered to. |
| Product Disclaimer | This product is provided for research only, not suitable for human or animal use. Due to the inherent limitations of infectious agent testing, investigators must exercise extreme caution when handling cells provided by Creative Biolabs, treating all cells as potentially biohazardous. |
| Target | ST6GALNAC1 |
| Full Name | ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 |
| Alternative Name | SIAT7A; ST6GalNAcI |
| Location | 17q25.1 |
| Gene ID | 55808 |
| Summary | Transfers sialic acid to O-linked GalNAc residues, forming the cancer-associated sialyl-Tn antigen and affecting cell-cell interactions. |