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Recombinant Mouse Aggrecan (ACAN) protein (Pro34-Glu147) [His-Tag], E. coli

CAT#: GP01-005J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant Mouse Aggrecan (ACAN) protein (NP_031450.2) (Pro34-Glu147) was expressed in E. coli with a His-Tag at the N-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
E. coli
Species
Mouse
Fragment
Pro34-Glu147
Sequence
MGHHHHHHSGSEFPQPSPLKVLLGSSLTIPCYFIDPMHPVTTAPSTAPLTPRIKWSRVSKEKEVVLLVATEGQVRVNSIYQDKVSLPNYPAIPSDATLEIQNLRSNDSGIYRCEVMHGIEDSEATLE
Tag
His-Tag at the N-terminus
Predicted MW
14.1 KDa
Purity
>95%, determined by SDS-PAGE and HPLC
Endotoxin Level
<1 EU/μg, determined by the LAL method
Conjugation
Unconjugated
Target Information
Target
ACAN
Full Name
Aggrecan
Gene ID
11595
Uniprot ID
Q61282
Accession Number
NP_031450.2
Background
Aggrecan is the major proteoglycan in the articular cartilage. This molecule is important in the proper functioning of articular cartilage because it provides a hydrated gel structure (via its interaction with hyaluronan and link protein) that endows the cartilage with load-bearing properties.
Alternate Names
Agc; Csp; Cmd; Agc1; CSPCP; Cspg1; b2b183C; b2b183Clo; ACAN; aggrecan
For Research Use Only.
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