Chitosan (VAdv-Ly0024)
| CAT | Size | Price | Quantity | |
|---|---|---|---|---|
| VAdv-Ly0024 |
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Chitosan, the deacetylated derivative of chitin, a NLRP3 inflammasome inducer.
Datasheet
Specifications
Type
PRRs Agonist
Molecular Weight
60-120 kDa
Specificity
Th1/Th2 response
Product Form
White solid
Endotoxin
Lower than 5 EU/mg.
Storage
Store at 2 to 8°C.
Shelf Life
2 years.
Adjuvant Information
Introduction
Chitosan is the deacetylated derivative of chitin, a polysaccharide found in the exoskeletons of crustaceans and in the cell walls of fungi. In addition to its role in drug delivery, chitosan acts as an adjuvant, owning to its immunostimulatory activity. Chitosan stimulates the immune system by activating the NLRP3 inflammasome, leading to potent IL‑1b production. When tested in experimental models of vaccination, chitosan elicits a balanced Th1/Th2 response.
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
